Aurelio Leone* Pages 3205 - 3216 ( 12 )
Background: Three types of necrosis characterize MI: coagulation necrosis, typically due to a coronarogenic mechanism, coagulative myocytolysis with formation of contract bands as an effect of sympathetic nervous system and adrenergic stimulation, and colliquative myocytolysis, characterized by myocardial fiber lysis, which is a close result of hydrolytic enzyme activity deriving from the material reaching the infarct area.
Methods: Although a multifactorial etiology may be identified, nevertheless coronary alterations, which are a consequence of atherosclerotic plaque formation and complications with a reduced blood flow supply to the myocardium, are the benchmark of MI. Results: Evidence indicates a close relationship between the MI and some coronary risk factors, associated with this pathologic pattern with a different, but high rate. Conclusion: Precipitating events to cause acute myocardial pathology need, however, to develop an acute myocardial infarction.Myocardial infarction, coronary pathology, sympathetic nervous system, catecholamine release, myocardial necrosis, coronary risk factor(s).
Castelnuovo Magra