Małgorzata Nita and Andrzej Grzybowski Pages 639 - 654 ( 16 )
Background: Tobacco smoking has detrimental influence on human health.
Aim: The analysis of influence of tobacco smoking on retina diseases, uveitis, optic neuropathies, and thyroidassociated orbitopathy in adults and children. Methods: A comprehensive review of the literature performed through MEDLINE and PubMed searches, covering the years 2000-2016. Results: In adults, tobacco smoking is a strong risk factor for age-related macular degeneration, polypoidal choroidal vasculopathy, uveitis and inflamed cystoid macular edema as well as Grave`s ophthalmopathy. Tobacco smoking reduces thickness of the retina and choroid, plays a role in episcleritis, sclerits, tobacco optic neuropathy, and Leber's hereditary optic neuropathy. In children, maternal smoking is a significant risk factor for stages 3 and 4 retinopathy of prematurity, optic nerve hypoplasia among babies with a birth weight over 2500 g and thinner retinal nerve fiber layer. Conclusion: Tobacco smoking plays an important role in the pathogenesis of many posterior eye segment diseases leading to blindness in adults and children.Tobacco smoking, retinopathy, ocular inflammation, optic neuropathy, orbitopathy, adults, children.
Domestic and Specialized Medicine Centre , Jozef Strus Poznan City Hospital, Department of Ophthalmology, 3 Szwajcarska St, 361-285 Poznan