Ariel R. Guerrero, Felipe Oyarzun-Ampuero, Natalia Hassan, Alejandro H. Corvalan, Andrew F.G. Quest and Marcelo J. Kogan Pages 5988 - 5997 ( 10 )
In recent years, advances in nanotechnology have raised the specter of developing effective agents for the treatment of high-impact diseases, like gastric cancer, which remains one of the major causes of cancer deaths worldwide. This article reviews advances in the treatment of this pathology using several types of nanoparticles. First, we start with an overview of gastric cancer, its prevention, detection and the available treatments. Then, we discuss nanotechnology-based novel strategies using polymeric nanosystems, nanovesicular systems and inorganic nanoparticles. All of these systems are being evaluated in the perspective of improving the targeting of anticancer drugs and reducing their negative side effects.
Nanoparticles, nanocarriers, gastric cancer, treatment, drug delivery, targeting.
, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile. Santos Dumont 964, Independencia, Santiago,, , , , Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile. Santos Dumont 964, Independencia, Santiago