Targeting the Assembly of the Human Immunodeficiency Virus Type I

Author(s):

D. Muriaux, J. L. Darlix and A. Cimarelli   Pages 3725 - 3739 ( 15 )

Abstract:

In the rush to develop anti-viral drugs against the human immunodeficiency virus type I (HIV-1), all the steps of the viral life cycle are potential targets of therapeutic intervention. In this review, we will explore the recent advances on strategies that aim at obstructing the formation, the release and the infectivity of newly formed virion particles from HIV-1 infected cells.

Keywords:

drugs,anti-viral approaches,virion assembly,hiv-1,retrovirus

Affiliation:

, , LaboRetro, Unite de Virologie Humaine. INSERM &#412, Ecole Normale Superieure de Lyon, 46 Allee d'Italie, 69364 Lyon cedex, France.

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