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Luminescent G-quadruplex Probes

[ Vol. 18 , Issue. 14 ]

Author(s):

Dik-Lung Ma, Daniel Shiu-Hin Chan, Hui Yang, Hong-Zhang He and Chung-Hang Leung   Pages 2058 - 2075 ( 18 )

Abstract:


G-quadruplexes have found increasing potential in applications such as molecular therapeutics, diagnostics, and sensing. As a consequence, small molecules capable of selectively detecting G-quadruplexes have received significant attention in recent literature. Our review here addresses representative advances in the development of luminescent G-quadruplex probes and highlights their potential applications in sensing and imaging.

Keywords:

G-quadruplex, DNA, small molecules, luminescent probes, detection, diagnostics, telomere, topologies, propeller, emission

Affiliation:

Department of Chemistry, Hong Kong Baptist University, Hong Kong.



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