Xiongpiao Wei, Dang Fan, Haifeng Dong, Min Li, Qiaoli Lv*, Pengwu Zheng* and Linxiao Wang* Pages 1520 - 1536 ( 17 )
Pyrido[2,3-d]pyrimidine and its derivatives have garnered significant attention due to their potential biological and pharmacological activities. Research has demonstrated their significant potential for antitumor and antibacterial applications. Over the years, pyrido[2,3-d]pyrimidine derivatives have remained a research focus for scientists, with numerous synthetic methods and reaction conditions reported. This review comprehensively summarizes the fast, facile, and economical synthetic methods for pyrido[2,3-d]pyrimidine derivatives over the past years, which are categorized based on different synthetic precursors, and evaluates their antitumor and antibacterial activities, aiming to make them better serve the cause of human health.
Pyrido[2,3-<i>d</i>]pyrimidine, one-pot multi-component reaction, antitumor, antibacterial, kinase inhibitors, pyridine derivatives.