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Models for Non-Alcoholic Fatty Liver Disease: A Link with Vascular Risk

[ Vol. 14 , Issue. 4 ]

Author(s):

A. K. Burroughs, E. Xirouchakis, A. Sigalas, P. Manousou, V. Calvaruso, M. Pleguezuelo, A. Corbani, S. Maimone and D. Patch   Pages 378 - 384 ( 7 )

Abstract:


Non alcoholic fatty liver disease (NAFLD) is often part of the metabolic syndrome which includes central obesity, dyslipidaemia, insulin resistance/type 2 diabetes mellitus and hypertension. In turn, NAFLD may be associated with an increased vascular risk. Several experimental models which express histological steatosis or steatohepatitis with fibrosis have been described. This review identifies those models of NAFLD with features of vascular risk.

Keywords:

Non-alcoholic fatty liver disease,non-alcoholic steatohepatitis,vascular risk

Affiliation:

, , , , , , , , Liver Transplantation and Hepatobililary Medicine, Royal Free Hospital, Pond Street, Hampstead,London NW3 2QG, UK.



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