Call for Papers  

Article Details


Cell Death in the IPLB-LdFB Insect Cell Line: Facts and Implications

[ Vol. 14 , Issue. 2 ]

Author(s):

D. Malagoli   Pages 126 - 130 ( 5 )

Abstract:


The present review summarizes findings on stress-induced cell death in the IPLB-LdFB insect cell line derived from the larval fat body of the lepidopteron Lymantria dispar. Apoptotic, oncotic and autophagic cell death have been described in these cells as a consequence of oxidative stress or ATP deprivation, and similarities between IPLB-LdFB and mammalian apoptotic pathways have been highlighted. Furthermore, starting from observations in the IPLB-LdFB cells, a link has been surmised between relevance of autophagic cell death and developmental processes in the metazoan taxa.

Keywords:

IPLB-LdFB insect cell line,Apoptosis,Oncosis,Autophagic cell death

Affiliation:

Department of Animal Biology,University of Modena and Reggio Emilia, via Campi 213/D, 41100 Modena, Italy.



Read Full-Text article