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Looking Back at Cannabis Research

[ Vol. 6 , Issue. 13 ]

Author(s):

Raphael Mechoulam   Pages 1313 - 1322 ( 10 )

Abstract:


Research leading to the isolation of the plant cannabinoids during the 1960s and to the endogenous cannabinoids, during the 1990s is described. Investigations on two non-psychotropic, synthetic cannabinoids, HU-211, a neuroprotective agent and HU-308, a specific CB 2 agonist are presented.

Keywords:

Cannabis,Plant cannabinoids,Endogenous cannabinoids,Non-psychotropic,Synthetic cannabinoids,HU-211,Neuroprotective,HU-308,CB2 agonist,Cannabidiol (CBD),Spectroscopy,NMR,Cannabinoids,Geranyl pyrophosphate,Cannabigerol,Cannabigerolic acid,Cannabidiol,Cannabidiolic acid,Cannabichromene,Cannabichromenic acid,Cannabielsoic acid A,Cannabinolic acid,Cannabinol,Cannabicylol,D9-THC,D8-THC,Anandamide,2-arachidonoyl-glycerol (2-AG),HU-211 (DEXANABINOL),NMDA receptor,HU-211 DRUG DEVELOPMENT,Synthesis of HU-308,APPETITE,AIDS,commercial name dronabinol

Affiliation:

Hebrew University,Medical Faculty, Department of Medicinal Chemistry and NaturalProducts, Jerusalem 91120, Israel



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