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DNA-Photocleavage Agents

[ Vol. 7 , Issue. 17 ]

Author(s):

Tatiana Da Ros, Giampiero Spalluto, Alexandre S. Boutorine, Rene V. Bensasson and Maurizio Prato   Pages 1781 - 1821 ( 41 )

Abstract:


This review describes recent advances in the development of DNA- photocleavage agents. Major mechanisms of photosensitized DNA photocleavage are presented and the most popular categories of compounds are considered, which include metal complexes and many organic functional derivatives. DNA-targeted conjugates of photosensitizers are also described and discussed.

Keywords:

Affiliation:

, , , , Dipartimento di Scienze Farmaceutiche - Piazzale Europa 1, I-34127 Trieste, Italy.



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